2231–4202  (Print)                
2249–9970  (Online)             
Peer Reviewed and Refereed Journal

JPAST is a Peer Reviewed & Refereed biannual multidisciplinary journal starting from July 2011. Articles are invited for Dec 23 issue.
Volume 12, Issue 2, Pages 1-31, July 2022

Insulin-Mediated Signaling Pathways in Healthy State and Insulin Resistance State

Prof. (Dr.) Anil Gupta

Vice-principal, Professor and Head, Department of Biochemistry

Eklavya Dental College and Hospital, Kotputli, Rajasthan, India

Global burden of type 2 diabetes mellitus is the main focus of the research studies in the world to understand fine details of normal metabolic and Mitogenic actions of insulin coupled with minute knowledge of the molecular causes of the insulin resistance and defect in the insulin signaling pathways that contribute to impaired carbohydrate metabolism in body. This review article provides thorough description of the insulin mediated signaling pathways and role of implicated effector molecules that are part of impaired signaling pathways to reach a consensus helpful in developing newer diagnostic as well as therapeutic molecules.

Keywords: Type 2 diabetes, insulin resistance, insulin actions, insulin signaling, impaired insulin signaling.

Full Paper

Copyright ©2011 NLSS all rights reserved Website Designed & Website Developed By Sunisht Technologies