Comparative Efficacy of Anthelmintic Resistance in Goat in Sylhet, Bangladesh
Dr. Suman Kumar Singh1,*, Prof. Dr. Md. Rafiqul Islam2 and Dr. Md. Tanvir Hasan3
1,*Department of Medicine, Faculty of Veterinary and Animal Science, Sylhet Agricultural University, Bangladesh. Email : modern_suman@yahoo.com
2Chairman, Department of Medicine, Faculty of Veterinary and Animal Science, Sylhet Agricultural University, Bangladesh.
3Department of Medicine, Faculty of Veterinary and Animal Science, Sylhet Agricultural University, Bangladesh.
A study is conducted to determine and compare the efficacy of different anthelmintics against gastrointestinal nematodes in naturally infected goats in Sylhet goverment goat development farm. About 60 male goats are divided into four groups of 15 animals each: the 1st group served as the untreated control, the 2nd was treated with albendazole, the 3rd with levamisole and the 4th with ivermectin. Faecal samples are collected on day 0 before treatment and again day on 12 post treatment. Efficacy for each anthelmintic is determined by the Faecal Egg Count Reduction Test (FECRT). About 100% efficacy against strongyle and Trichuris sp. is recorded in goats treated with albendazole and ivermectin. On the contrary, low efficacy of 86.7% is observed in goats treated with levamisol. Likewise, low efficacy of 66.7%, 40% and 46.7% against Moniezia sp. is recorded in goats treated with albendzole, levamisol and ivermectin, respectively. Coprocultures from all both pre and post-treatment samples revealed the pre-dominance of Haemonchus sp. The results of the study showed the presence of inverse relationship between the body condition score and their respective mean EPG (R2 = 0.99), suggesting the negative effect of parasitic load on the performance of goats. A questionnaire survey conducted to gather information on methods of control practices of nematodes of goats revealed lack of basic awareness among owners of goats about the best use and efficacy of anthelmintics. In addition, it indicated that farmers in the study area apply many practices that may lower the efficacy of anthelmintics and favor the emergence of anthelmintic resistance. Benzimidazoles group of anthelmintics were reported to be used at the most frequency followed by imidazothiazoles and the avermectins are used at lowest frequency.
Keywords: Anthelmintics, Gastrointestinal nematodes, Albendazole, Levamisol, Ivermectin, Faec`al Egg Count Reduction Test (FECRT), Strongyle and Trichuris sp., Moniezia sp., Haemonchus sp.
