JPAST is biannual multidisciplinary journal starting from July 2011. Articles are invited for July 20 issue.
Prospective Cohort Study to Evaluate Hyponatremia as a Sequela of Acute Renal Dysfunction in Cirrhosis of Liver – Dr. Anil Gupta.

Prospective Cohort Study to Evaluate Hyponatremia as a Sequela of Acute Renal Dysfunction in Cirrhosis of Liver

Dr. Anil Gupta

 Senior Lecturer, Deptt. of Physiology and Biochemistry, Eklavya dental College, Rajasthan, India.

 

Hyponateremia is a medical condition commonly seen in patient with progressive cirrhosis. The study was conducted on total 30 cirrhotic patients. Group 1 showed mean eGFR (93.9 ± 12 ml/min/1.73m2) by simplified MDRD equation, significantly (p<0.001) above reference value (75 ml/min/1.73m2) as agreed upon, lower normal value as per RIFLE classification. Group 2 showed mean eGFR (48.8 ± 14.7 ml/min/1.73m2) significantly (p<0.001) below the normal reference value.

full paperFull Paper


Metabolic Syndrome: The Prevalence of Mounting Public Health Problem in Ghaziabad, India – Himanshu Tyagi, Vishal Modgil and Mahendra Nath.

Metabolic Syndrome: The Prevalence of Mounting Public Health Problem in Ghaziabad, India

Himanshu Tyagi1,*, Vishal Modgil2 and Mahendra Nath3

1,*Ph.D. Scholor, Medical Biochemistry, Shivalik Hospital, Ghaziabad, India.

2Department of Medicine, Shivalik Hospital, Ghaziabad, India.

3L.L.R. Medical College, Meerut, India.

Metabolic syndrome (MetS) is a name for a group of risk factors that occur together and increases the risk for coronary artery disease, stroke, and type 2 diabetes. The MetS is a clustering of components that reflect over nutrition, sedentary lifestyles and resultant excess adiposity. Metabolic Syndrome is posing a major public health challenge to the health systems in developed and developing countries. The 405 study subjects aged between 25-65 yrs from general population in Ghaziabad, India, were taken, who attended the hospital for general checkup. Complete fasting lipid profile, Blood glucose, and Hs-CRP, Lp(a) and GGT, blood urea and Serum Creatinine of subjects were evaluated. On application of ATP 3rd criteria on the screened subject patients, they are classified. Our study found that the number of subjects having MetS was 173 (42.71% of total). In the subgroup of metabolic syndrome with diabetes, the total number of subjects was 105(25.92%) in which age wise distribution was 26 (6.41%) in 25-45 yrs and 79 (19.50%) in 45-65 yrs. In the second subgroup of metabolic syndrome without diabetes total number of subjects was 68 (16.79%) in which age wise distribution was 16 (3.95%) in 25-45 yrs and 52 (12.83%) in 45-65 yrs. The study proposes the inclusion of biochemical parameter Hs-CRP, Lp (a) and GGT in the criteria for defining cases of metabolic syndrome, so that more metabolic syndrome cases can be picked up at earliest. This issue is especially pertinent for the Indian patient population in whom cardiovascular disease is becoming increasingly common in both sexes and in age group of 25-65 yrs. There should be emphasis on detection of metabolic syndrome and intensification of targeted preventive strategies.

full paperFull Paper


Prospective Study to Evaluate Anemia and its Covariation with Hypoalbuminemia in Patients Suffering from Ascites Cirrhosis – Dr. Anil Gupta.

Prospective Study to Evaluate Anemia and its Covariation with Hypoalbuminemia in Patients Suffering from Ascites Cirrhosis

Dr. Anil Gupta

 Senior Lecturer, Deptt. of Physiology and Biochemistry, Eklavya dental College, Rajasthan, India.

 

Anemia is the reduction in quantity of haemoglobin pigment in circulating blood. It is the manifestation of chronic inflammation, infection or malignancy in the body. The study sample comprised of total 30 participants in two groups. The mean haemoglobin of cirrhotics (9.86 ± 1.8 mg/dl) was lesser in comparison to haemoglobin (13.09 ± 1.76 mg/dl) of controls significantly (p<0.0001). Further, sample t-test revealed a significant (p<0.0001) reduction in concentration of haemoglobin of cirrhotics at a cut off (13 mg/dl). The anemia in cirrhotics covariated significantly (p=0.05), with hypoalbuminemia, as revealed in Pearson’s coeffiecient of correlation (r=0.043).

full paperFull Paper


Assessment of Drinking Water Quality at three Intermediate Colleges and two Degree Colleges of Municipality of District Sambhal, U.P., India – Sushil Kumar and Himshikha Yadav.

Assessment of Drinking Water Quality at three Intermediate Colleges and two Degree Colleges of Municipality of District Sambhal, U.P., India

Sushil Kumar1,* and Himshikha Yadav2

1,*Asst. Prof. and Head, Department of Zoology,Govt. Degree College Sambhal, Moradabad, India.

2Asst. Prof. and Head, Department of Botany, Govt. Girls (P.G.) College, Bareilly, India,

 

The paper reports drinking water quality from three inter colleges and two degree colleges of Sambhal municipality. The quality of drinking water samples were assessed by examining various physico-chemical and biological parameters viz, colour, odour, taste, turbidity, pH, specific conductivity, total dissolved solids, total hardness,  chloride, fluoride, sulphate, nitrate, calcium, magnesium, dissolved oxygen (DO) and total coliforms. The analytical results were compared with drinking water standard (BIS-10500) prescribed by Bureau of Indian Standard, New Delhi. The water quality in general found to be satisfactory but the level of total hardness, chloride, nitrate, and magnesium were slightly higher at some locations and coliforms contamination was also found in some of drinking water samples.

full paperPart 1

full paperPart 2

full paperPart 3

full paperPart 4


Isolation and Partially Characterization of Bacteriocin Produced by Lactic Acid Bacteria Isolated from Barley Beer – Dr. Mukta Sharma and Dr. Anandveer Singh.

Isolation and Partially Characterization of Bacteriocin Produced by Lactic Acid Bacteria Isolated from Barley Beer

Dr. Mukta Sharma1,* and Dr. Anandveer Singh2

1,*Prof. & Head, Departt. of Microbiology, S.B.B. Dental College & Research Centre, Masuri, Ghaziabad, India.

2Department of Chemistry, BSA College, Mathura, India.

 

Twenty lactic acid bacteria (LAB) were isolated from barley beer, six of these beer isolates were observed to secrete the inhibitory compounds into the cell-free filtrate with optimal production occurring in the late exponential growth phase. The inhibitory spectra of these isolates included various Gram’s positive and Gram’s negative bacteria and a variety of beer-spoiling bacteria. Based on standard biochemical and microbiological tests, these isolates were tentatively identified as Lactococcus lactis subsp. lactis, Lactobacillus sakei, Lactobacillus brevis, Lactobacillus plantarum, Lactobacillus pentosus, Lactobacillus paracasei. These inhibitory isolates were inactivated by treatment with proteolytic enzymes indication that the inhibitory compound was proteinaceous in nature, the proteinaceous nature and inactivation by catalase identified them as bacteriocins. These bacteriocins were partially characterized. Bacteriocins produced by these six isolates were active across a wide pH range, relatively insensitive to heat treatment. Stability of the secreted bacteriocins at varying pH values indicated that full activity was retained in all samples at pH 4-6 with a significant reduction in activity at pH 2-3 and pH 7-10.

full paperFull Paper


Absorption Studies of Tripositive Neodymium Doped Lithium Bismuth Borate Glasses – B. Bhatia and V. Parihar.

 

 

Absorption Studies of Tripositive Neodymium Doped Lithium Bismuth Borate Glasses

B. Bhatia1,* and V. Parihar2

1,*, 2Ceramic Laboratory, Department of Physics, Jai Narain Vyas University Jodhpur 342001(Raj.)India

  

Glasses having composition (60-x) B2O3-10Bi2O3-30Li2O-xNd2O3 with x =1, 1.5 and 2 were prepared by melt quenching technique. The amorphous nature of the prepared glass samples was confirmed by X-ray diffraction. The absorption spectra of three Nd3+ lithium bismuth borate (LBB) glasses have been recorded at room temperature. From these spectral data various energy interaction parameters like Slater-Condon parameters Fk (k=2, 4 and 6), Lande’ parameters x4f and Racah parameters Ek (k=2, 4 and 6) have been computed. Nephelauxetic ratio (β’) and bonding parameters (b1/2) have also been computed from these parameters to study the nature of bonding in doped glasses. The intensities of the f-f transitions in the absorption spectra have been analyzed by the application of the Judd-Ofelt theory.

full paperFull Paper


A combined approach of Swarm Intelligence Protocols for Monitoring Network Congestion – Rashmi Singh and Dr. Sweta Verma.

 

A combined approach of Swarm Intelligence Protocols for Monitoring Network Congestion

Rashmi Singh1,* and Dr. Sweta Verma2

1,*Research Scholar, New Delhi, India

2Department of Information Technology, Galgotia’s College of Engg & Technology

Greater Noida, India

 

This paper introduces a hybrid technique by combining more than one protocols of swarm intelligence to obtain better network traffic management. The proposed routing protocol which is a combination of Wireless Ant Network based Routing Protocol (W_AntNet), named as Secure Load Aware Wireless Ant Network (SLAWAN) and Bee Hive based Routing Algorithm for decreasing route discovery latency in real time communications in high dynamic networks. The proposed algorithm splits the network into two parts; one is a fixed network and the other is a mobile ad hoc network (MANET), then applying the Wireless Ant Network based Routing Algorithm on the mobile part and the Bee Hive based Routing Algorithm on the fixed one. This protocol monitors the congestion status of active routes and reconstructs the path when nodes of the route have their network buffer queue overloaded.

full paperFull Paper

 


A Morphology based Approach for Human Skin Detection in Color Image – Lavanya Sharma, D.K. Yadav and Manoj Kumar.

A Morphology based Approach for Human Skin Detection in Color Image

Lavanya Sharma1,*, D.K. Yadav2 and Manoj Kumar3

1,2,3Department of CSE, M.R.C.E. Faridabad, India

 

A reliable skin detection method that is adaptable to different human skin colors and illumination is very essential for human skin detection. Today’s many skin detection methods are available in literature but they are not able to cope with variety of skin colors. Several image processing and computer vision approaches have been developed for human skin detection. In this work we propose a mathematical morphology based YCbCr method which given better performance as compare to other HSV, YCbCr color spaces. This method is simple and efficient. The experimental result shows that the proposed method can achieve satisfactory performance in real time applications.

full paperFull Paper


Spectroscopic Investigation of Pr3+ Doped Zinc Lithium Bismuth Borate Glasses – Beena Bhatia and Vishal Parihar.

Spectroscopic Investigation of Pr3+ Doped Zinc Lithium Bismuth Borate Glasses

Beena Bhatia1,* and Vishal Parihar2

1,2Ceramics Laboratory, Department of Physics, Jai Narain Vyas University, Jodhpur-342001(Raj.), India

 

Optical absorption and fluorescence spectra of Pr3+ doped bismuth borate glasses having glass system (60-x)B2O3-10Bi2O3-20Li2O-10ZnO-xPr6O11 where x=1, 1.5 and 2 mol% have been recorded. Judd-Ofelt theory have been applied to compute oscillator strength and intensity parameters Ωλ (λ=2, 4 and 6).  These parameters have been used to calculate the radiative properties of glasses viz., spontaneous emission probability (A), radiative life time (tR), fluorescence branching ratio (βR) and stimulated emission cross section (σp) of various emission lines have been evaluated. The results obtained suggest that these new materials can be considered as an interesting candidate for laser applications.

full paperFull Paper


Vitamin C Source Food Articles, Cure of Urinary Tract Infection in North India – A.S. Shishodia, Dr. Mukta Sharma and Ajit Joshi.

Vitamin C Source Food Articles, Cure of Urinary Tract Infection in North India

A.S. Shishodia1, Dr.  Mukta Sharma2,* and Ajit Joshi3

1,3Department of Microbiology, Mewar University, Chittorgarh (Raj.), India

2,*Department of Microbiology, S.B.B. Dental College & Research Centre, Ghaziabad, India

 

Different bacterial strains were isolated from hospitalized patients with Urinary Tract Infection and microscopically and biochemically characterized as Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis Streptococcus sp., Staphylococcus saprophyticus and Alcaligenes   faecalis. Klebsiella pneumoniae was the most common urine isolate and Staphylococcus saprophyticus was another common organism. The antimicrobial activity of vitamin C sources like cranberry, amla, lemon, roseberry and mango was determined against a total of forty eight isolated organisms by well plate method and sensitivity of antibiotics were also checked by Kirby-Baur disc diffusion method. On comparative analysis of vitamin C source food articles and antibiotic sensitivity against isolated organisms it was found that action of cranberry, amla, lemon, roseberry and mango have good effect as compare to different antibiotics. Among these sources cranberry was most effective against all urine isolates. Due to the emergence of drug resistant microorganisms, it is a need to search out more effective antimicrobial agents to cure the disease. Our studies suggest that high intake of vitamin C tends to increase the acidity of urine which is not well tolerated by the bacteria responsible for UTI.

full paperFull Paper


A Mössbauer Spectroscopic study of Ordinary Chondrites – Abhijit Kulshreshtha and Neeraj Bijlani.

A Mössbauer Spectroscopic study of Ordinary Chondrites

Abhijit Kulshreshtha1 and Neeraj Bijlani2,*

1,2,*Department of Physics, Jodhpur National University, Jodhpur, India

 

Mössbauer spectroscopic studies of Ordinary chondrite shows that the main iron minerals in chondrites are Fe-Ni (Kamacite/Taenite), Troilite, Olivine and Pyroxene. Presence of these minerals can be characterized as a signatures of ordinary chondrites. Mössbauer absorption areas corresponding to different phases favour its classification as H ordinary chondrites.

full paperFull Paper


A Comparative Study of Novel Super Disintegrating Agent, Guar gum to existing Super Disintegrating Agent, Sodium Starch Glycolate on Release Rate of Drug from Fast Dissolving Tablet – Dr. Rambabu Sharma, Deepak Choudhary, Anil Bhandari, Rajesh Verma and M.S. Ranawat.

A Comparative Study of Novel Super Disintegrating Agent, Guar gum to existing Super Disintegrating Agent, Sodium Starch Glycolate on Release Rate of Drug from Fast Dissolving Tablet

Dr. Rambabu Sharma1, *, Deepak Choudhary2,  Anil Bhandari3, Rajesh Verma4 and M.S. Ranawat5

1,2,3,4Faculty of pharmaceutical science, Jodhpur National University, Jodhpur, India.

5B. N. College of Pharmacy, Udaipur. India.

 

The aim of present study is to exist a novel super disintegrants in fast dissolving tablet. Guar gum is a natural substance and used in many pharmaceutical product and it can also used as a super disintegrating agent in fast dissolving tablet. The result is that it released the 99.21% drug in 15min as compared to Sodium Starch Glycolate (SSG), where only 97.51% drug was released. The onset of time was better for guar gum where, 84.79% of drug was released in 2min from F3 formulation as compared of F6 formulation where only 71.22% drug was released.  The possible mechanism of disintegrating property was good swelling property of guar gum than SSG but when the concentration of guar gum was used above 8%, it created a problem on disintegration of tablet due to formation of gel layer around the tablet. All evaluating parameters were within range and no markedly difference was observed.

full paperFull Paper


An Overview of LTE Technology and its Applications in Telecommunication Domain – Ritesh Saraswat, Dr. Sarika Jain, Dr. Vijay Kaushik and Charu Jain.

An Overview of LTE Technology and its Applications in Telecommunication Domain

Ritesh Saraswat1,*, Dr. Sarika Jain2, Dr. Vijay Kaushik3 and Charu Jain4

1,*Research Scholar, Department of Electronics, CMJ University, Meghalaya, India

2HOD, Department of Electronics, VIIT, Bulandshahr, UP, India

3Director, Department of Electronics, VIIT, Bulandshahr, UP, India

4Lecturer, Department of Mgmt. & Comp. Sc., R.V. Higher Edu. & Tech. Institute, Dadari, G.B. Nagar, UP, India

 

Various wireless access technologies i.e. both the non-3GPP and 3GPP are beyond the Long Term Evolution (LTE) and connected to the Evolved Packet Core System (EPC), for example Wi-Fi (Wireless Fidelity). The wireless access technologies predicted that mobile data traffic may increase the high capacity demands. The improved device capabilities and new services indicates that the consumer data-rate and mobile broadband traffic demands are growing at an unprecedented rate. The mobile broadband traffic are increased at high rate and the Ericsson reports specify that world total mobile data traffic in 4G, 3G and 2G networks will have possibilities to grow 10-fold between 2011 and 2016.

full paperFull Paper


Impact on the Phenological Events of Plants under Stress Conditions of Auto-Exhaust Pollution – Dr. Anita Pawar.

Impact on the Phenological Events of Plants under Stress Conditions of Auto-Exhaust Pollution

Dr. Anita Pawar

Asst. Prof. Department of Botany

N.R.E.C. College, Khurja, U.P., India

Present paper deals with the impact of auto-exhaust pollution on the phenological events of Withania somnifera and Amaranthus viridis growing along the road side. For study purpose three sites were identified i.e Highly Polluted Area (HPA), Medium Polluted Area (MPA) and Fresh Area (FA-Control), in city Ghaziabad which is an important industrial town of western U.P.. Various phenological events like-germination, vegetative growth, flowering and fruiting etc. were recorded. It was found  that different plants respond differently to the stress and life cycle was noticed short under stressed conditions of pollution.

full paperFull Paper